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ACYCLOVIR

Acyclovir or generic Zovirax - Oral pills are used to treat initial genital herpes infections and to treat patients with recurrent (6 episodes per year) severe genital herpes. This medicament reduces the pain and the number of lesions in the initial case, and decreases the frequency and severity in those with recurrent infections. In the treatment of shingles, it reduces pain, shortens the healing time, and limits the spread of virus and the formation of new lesions. Acyclovir can be used to treat chicken pox and acts to reduce healing time, limit the number of lesions, and reduce fever if used within the first 24 hours after the onset of the disease. Acyclovir ointment is used topically to treat initial genital herpes where it has been shown to decrease pain, reduce healing time, and limit the spread of the infection.

DRUG INTERACTIONS: Genital herpes is a sexually transmitted disease and patients should avoid intercourse when they have visible lesions. Resistance to acyclovir can develop, especially with overuse. Therefore, this medicine should be used only for severe cases and only as long as needed. Long-term suppression for recurrent genital herpes should include periodic re-evaluations and trials without the drug or intermittent short-term treatments.

SIDE EFFECTS: Rare side effects in patients treated short-term with acyclovir are nausea, vomiting, and headache. Long-term treatment has the additional potential for rash and diarrhea.