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ADVAIR

Advair, the combination of fluticasone and salmeterol, is used to prevent wheezing, shortness of breath, and breathing difficulties caused by asthma. Fluticasone is in a class of medications called steroids. Advair works by reducing swelling in the airways. Salmeterol is in a class of medications called long-acting beta-agonists. This medicament works by relaxing and opening air passages in the lungs.

Advair Diskus is an inhaled drug that is used to treat asthma and chronic bronchitis. In patients with asthma, the airways through which air moves in and out of the lungs can be narrowed by accumulation of mucus, spasm of the muscles that surround these airways, or swelling of the lining of the airways due to inflammation. Airway narrowing leads to symptoms of shortness of breath, wheezing, cough and congestion. Medications used in treating asthma include those that open airways, called bronchodilators, and those that reduce the inflammation. Advair Diskus contains a combination of salmeterol, a bronchodilator of the beta-2 agonist type, and fluticasone propionate, an anti-inflammatory corticosteroid. Beta-2 agonists are medications that attach to beta-2 receptors on the smooth muscle cells that surround the airways, causing the muscle cells to relax and opening the airways. Fluticasone propionate is a synthetic (man-made) corticosteroid of the glucocorticoid family which is related to the natural hormone, cortisol or hydrocortisone, produced by the adrenal glands. Glucocorticoid steroids have potent anti-inflammatory actions. In asthmatic patients, the suppression of inflammation within the airways reduces the muscle spasm that narrows the airways. At the same time, swelling and mucus are reduced. When used in lower doses, very little fluticasone propionate is absorbed into the body. When higher doses are used, fluticasone is absorbed and may cause side effects elsewhere in the body.