COZAAR or generic Cozaar
- losartan - is indicated for the treatment of hypertension.
Cozaar is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is
evidence that this benefit does not apply to Black patients.
Cozaar is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin
to creatinine ratio ≥300 mg/g) in patients with type 2 diabetes and a history of hypertension.
HYZAAR or generic Hyzaar - losartan and hydrochlorothiazide - is used to treat high blood pressure. Hyzaar blocks the action of
certain chemicals that tighten the blood vessels so blood flows more smoothly. Hyzaar also causes the kidneys to get rid of unneeded
water and salt from the body into the urine. This fixed dose combination of losartan and hydrochlorothiazide is not indicated for
initial therapy of hypertension, except when the hypertension is severe enough that the value of achieving prompt blood pressure
control exceeds the risk of initiating combination therapy in these patients.
SIDE EFFECTS: In studies of over 4000 patients, including 1200
treated for over 6 months and 800 for over 1 year, the overall incidence
of side effects was similar to placebo. Losartan is generally well
tolerated. Side effects reported included diarrhea, muscle cramps,
dizziness, insomnia, and nasal congestion.
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