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TETRACYCLINE

Tetracycline is a broad-spectrum antibiotic. It is effective against a wide variety of bacteria including Hemophilus influenzae, Streptococcus pneumoniae, Mycoplasma pneumoniae, Chlamydia psittaci, Chlamydia trachomatis, Neisseria gonorrhoeae, and many others. The first drug of the tetracycline family, chlortetracycline, was introduced in 1948.

PRESCRIBED FOR: Tetracycline is used for many different infections including respiratory tract infections due to Hemophilus influenzae, Streptococcus pneumoniae, or Mycoplasma pneumoniae. The drug also is used for nongonococcal urethritis (due to Ureaplasma), Rocky mountain spotted fever, typhus, chancroid, cholera, brucellosis, anthrax, syphilis, and acne. Tetracycline is used in combination with other medications to treat Helicobacter pylori, the bacteria associated with ulcers of the stomach and duodenum.

DOSING: Tetracycline should be taken at least one hour before or two hours after meals to prevent binding to food and the resulting reduced absorption of the antibiotic. For most infections, it is taken two to four times daily for 7 to 14 days.

SIDE EFFECTS: It is generally well-tolerated. The most common side effects are diarrhea or loose stools, nausea, abdominal pain, and vomiting. Tetracyclines may cause discoloration of teeth if used in patients below 8 years of age. Exaggerated sunburn can occur with this antibiotic; therefore, sunlight should be minimized during treatment.